Organized by Topic


 Tissue Chips

  • Piazza, N., Dehghani, M., Gaborski, T.R., Wuertz-Kozak, K. (2020) Therapeutic Potential of Extracellular Vesicles in Degenerative Diseases of the Intervertebral Disc Frontiers in Bioengineering and Biotechnology 8, 10.3389/fbioe.2020.00311
  • Khire, T.S., Salminen, A.T., Swamy, H., Lucas, K.S., McCloskey, M.C., Ajalik, R.E., Chung, H.H, Gaborski, T.R., Waugh, R.E., Glading, A.J., McGrath, J.L., (2020) Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions  Cell and Molecular Bioengineering 13: 125–139
  • Hudecz, H., Khire, K., Chung, H.L., Adumeau, L., Glavin, D., Luke, E.N., Nielsen, M.S., Dawson, K.A., McGrath, J.L., Yan, Y. (2020) Porous Silicon Nitride Membranes for in situ Optical Analysis of Translocation of Nanoparticles across the Blood-Brain Barrier ACS Nano 141111-1122
  • Allahyari, Z, Gholizadeh, S. Chung, H.L., Delgadillo, L., Gaborski, T.R. (2020) Micropatterned PEG islands disrupt endothelial cell-substrate interactions differently from microporous membranes ACS Biomater. Sci. Eng. 6:959-968
  • Masters, E.A., Salminen, A.T., Begolo, S., Luke, E.N., Barrett, S., Overby, O.T., Gill, A.L., de Mesy Bentley, K.L., Awad, H.A., Gill, S.R., Schwarz,, E.S., McGrath, J.L. (2019) An in vitro platform for elucidating the molecular genetics of S. aureus invasion of the osteocyte lacuno-canalicular network during chronic osteomyelitis. Nanomedicine 21:102039
  • Salminen, A.T., Zhang, J., Madejski, G.R., Khire, T.S, Waugh, R.E., McGrath, J.L., Gaborski T.R.(2019) Ultrathin Dual-Scale Nano- and Micro-Porous Membranes for Vascular Transmigration Models. Small  5(6):e1804111
  • Mossu, A., Rosito, M., Khire, T., Chung, H.H., Nishihara, H., Gruber, I., Luke, E., Dehouck, L., Sallusto, F., Gosselet, F., McGrath, J.L., Engelhardt, B., (2019) A Silicon Nanomembrane Platform for the Visualization of Immune Cell Trafficking Across the Human Blood-brain Barrier Under Flow. Journal of Cerebral Blood Flow & Metabolism 39(3):395-410
  • Chung, H.H.; Bellefeuille, S. D.; Miller, H. N.; Gaborski, T. R., (2018) Extended Live-tracking and Quantitative Characterization of Wound Healing and Cell Migration with SiR-Hoechst. Exp Cell Res 373:198-210.
  • Chung, H.H., Casillo, S. M., Gaborski, T.R., (2018) Porous Substrates Promote Endothelial Migration at the Expense of Fibronectin Fibrillogenesis. ACS Biomater Sci Eng 4:222-230.
  • Chung, H.H. , Mireles, M. BJ Kwarta, TR Gaborski (2018) Use of Porous Membranes in Tissue Barrier and Co-culture Models. Lab on a Chip 18:1671-1689
  • Khire, T, Nehilla, B.J., Getpreecharsawas, J., Gracheva, M.E., Waugh, R.E., McGrath, J.L., (2018) Finite Element Modeling to Analyze TEER Values Across Silicon Nanomembranes, Biomedical Microdevices 20:1-11
  • Casillo, S. M., Peredo, A. P., Perry, S. J., Chung, H. H.; Gaborski, T.R., (2017) Membrane Pore Spacing Can Modulate Endothelial Cell-Substrate and Cell-Cell Interactions. ACS Biomater Sci Eng 3: 243-248.
  • Carter, R. N., Casillo, S. M., Mazzocchi, A. R.; DesOrmeaux, J. S., Roussie, J. A., Gaborski, T. R., (2017) Ultrathin transparent membranes for cellular barrier and co-culture models. Biofabrication 9: 015019.
  • Bentley, K., Trombetta, R., Nishitani, K, Bello-Irizarry, S.N., Ninomiya, M, Chung, H.L., McGrath, J.L., Daiss, J.L., Awad, A.A., Kates, S.L., Schwarz, E.M. (2017) Evidence of Staphylococcus aureus deformation, proliferation and migration in surgery-induced microcracks and canaliculi of live cortical bone in murine models of osteomyelitis. Journal of Bone and Mineral Research, 32:985-990
  • Mazzocchi, A. R.; Man, A. J., DesOrmeaux, J. P. S., Gaborski, T. R., (2014) Porous Membranes Promote Endothelial Differentiation of Adipose-Derived Stem Cells and Perivascular Interactions. Cel. Mol. Bioeng.  7 (3), 369-378.
  • Nehilla, B.J., Nataraj, N., Gaborski, T.R., McGrath, J.L. (2014) Endothelial Vacuolization Induced By Highly Permeable Nanoporous Substrates, Acta Biomaterialia 10:4670-4677
  • Chung, H.H., Chan, C.K., Khire, T.S., Clark Jr., A., Waugh, R.E., McGrath, J.L. (2014) Highly Permeable Silicon Membranes for Shear Fee Chemotaxis and Rapid Cell Labeling, Lab on a Chip 14:2456-68
  • Gaborski, TR, Miller, J., Striemer, CC, McGrath, JL (2013) Highly Permeable, Transparent and Degradable Membranes for Tissue Scaffolding, Microscopy and Microanalysis 19:8-9
  • Agrawal, A.A., Nehilla, B.J., Reisig, K.V. , Gaborski, T.R., Fang, D.Z, Striemer, C.C., Fauchet, P.M., and McGrath, J.L. (2010) Porous nanocrystalline silicon membranes as highly permeable and molecularly thin substrates for cell culture. Biomaterials 31: 5408-5417, PMCID: 2039892


  • Dehghani, M., Kilean Lucas, K., Flax, J., McGrath, J.L., Gaborski, TR., Tangential flow microfluidics for the capture and release of nanoparticles and extracellular vesicles on conventional and ultrathin membranes (2019) Advanced Materials Technologies, 4: 1900539
  • Smith, K.J.P., May, M., Baltus, R., McGrath, J.L., (2017) A Predictive Model of Separations in Dead-End filtration with ultrathin membranes, Separation and Purification Technology, 189:40-47
  • Winans, J., Smith, K., Gaborski, T.R., Roussie, J., McGrath, J.L., (2016) Membrane capacity and fouling mechanisms for ultrathin nanomembranes in dead-end filtration. J. Mem. Sci. 499: 282-289
  • Smith, K.J., J. Winans, and McGrath, J.L. (2016) Ultrathin Membrane Fouling Mechanism Transitions in Dead-End Filtration of Protein. in ASME  14th International Conference on Nanochannels, Microchannels, and Minichannels. American Society of Mechanical Engineers.
  • Kavalenka, MN, Christopher C.S., Fang, D.F., Gaborski, T.R., McGrath, J.L. and Fauchet, P.M. (2012) Ballistic and non-ballistic gas flow through ultrathin nanopores, Nanotechnology 23: 145706
  • Snyder, J.L., Clark Jr., A, Fang, D.Z., Gaborski, T.R., Striemer, C.C., Fauchet, P.M., McGrath, J.L. (2011) A theoretical and experimental analysis of molecular separations by diffusion through ultrathin nanoporous membranes J. Mem. Sci. 369:119-129, PMCID: 3032943
  • Gaborski, T.R., Snyder, J.L., Striemer, C.C., Fang, D.Z., Hoffman, M., Fauchet, P.M., and McGrath, J.L. (2010). High performance separation of nanoparticles using ultrathin pnc-Si membranes. ACS Nano 4:6973-6981
  • Ishimatsu, R., Kim, J., Jing, P., Striemer, C., Fang, D., Fauchet, P., McGrath, J.L. and Amemiya, S. (2010). Ion-Selective Permeability of Ultrathin Nanopore Silicon Membrane as Studied Using Nanofabricated Micropipet Probes. Analytical Chemistry 82:7127-34, PMCID: 2932823
  • Kavelenka, M., Fang, D.Z., Striemer, C.C., McGrath, J.L., and Fauchet, P.M. 2009. Hybrid polymer/ultrathin porous nanocrystalline silicon membrane system for flow-through chemical vapor and gas detection. In Material Research Symposium Proceedings (M.R. Society, ed.), vol. 1190. pp. 1190-NN1112-1103.
  • Kim, E., Xiong, H., Striemer, C., Fang, D., Fauchet, P., McGrath, J.L., Amemiya, S. (2008), “A structure-permeability relationship of ultrathin silicon nanoporous membrane: A comparison with the nuclear envelope.” Journal of American Chemical Society, 130: 4230-4231


  • Dehghani, M., Gulvin, S.M., Flax, J., Gaborski, T.R. (2020) Systematic Evaluation of PKH Labelling on Extracellular Vesicle Size by Nanoparticle Tracking Analysis Scientific Reports 10, 9533, 10.1038/s41598-020-66434-7
  • Lam M.L., Kyle, B, Konstantinos, K., Martin, M., Madejski, G.R., McGrath, J.L., Hendrick, d.H., Tabard-Cossa, V., Entropic Trapping of DNA with a Nanofiltered Nanopore (2019) ACS Applied Nanomaterials, 2:4773-4781
  • Madejski, G.R., Briggs, K., DesOrmeaux, J.P., Miller, J.J., Roussie, J.A., Tabard-Cossa, V., McGrath, J.L., (2019) Monolithic Fabrication of NPN/SiNx Dual Membrane Cavity for Nanopore-based DNA Sensing Advanced Materials Interfaces
  • Briggs, K, Madejski, G., G., Magill, M., Kastritis, K., de Haan, H. W., McGrath, J.L. and Tabard-Cossa, V., (2018) DNA Translocations Through Nanopores Under Nanoscale Pre-confinement, Nano Letters 8:660-668.
  • Kavalenka, MN, Striemer, CS, DesOrmeaux, JP, Fang, D, McGrath, JL, Fauchet, PF (2012) Chemical capacitive sensing using ultrathin flexible nanoporous electrodes, Sensors & Actuators B: Chemical, 162: 22-26


  • Miller, J.J., Carter, J.A., Hill, K., DesOrmeaux, J.P.S., Carter, R.N., Gaborski, T.R., Roussie, J.A., McGrath, J.L., Johnson, D.G. (2020) Free Standing, Large-Area Silicon Nitride Membranes for High Toxin Clearance in Blood Surrogate for Small-Format Hemodialysis  Membranes 10: 119
  • Hill, K., Walker, S.N., Salminen, A., Chung, H.L., Li, X., Ezzat, B., Miller, J.J., DesOrmeaux, J.P.S, Zhang, J., Hayden, A., Burgin, T., Piraino, L., May, M.N., Gaborski, T.R., Roussie, J.A., Taylor, J., DiVincenti Jr., L., Shestopalov, A.A., McGrath, J.L., Johnson, D.G (2020) Second Generation Nanoporous Silicon Nitride Membranes for High Toxin Clearance and Small Format Hemodialysis Advanced Healthcare Materials 9:1900750
  • Burgin, T., Johnson, D., Chung, H., Clark, A., and McGrath, J.L. (2015) Analytical and Finite Element Modeling of Nanomembranes for Miniaturized, Continuous Hemodialysis. Membranes 6: 6-20
  • Burgin, T., Johnson, D.G., Chung, H.L., Clark, A., McGrath, J.L., (2016) Ultrathin Silicon Membranes for Improving Extracorporeal Blood Therapies in ASME 2016 14th International Conference on Nanochannels, Microchannels, and Minichannels 2016. American Society of Mechanical Engineers.
  • Johnson, D.G., Pan, S., Hayden, A., McGrath, J.L., (2016) Nanoporous membrane robustness/stability in small form factor microfluidic filtration system. Engineering in Medicine and Biology Society (EMBC),  38th Annual International Conference.
  • Johnson, D.G, Khire, T.S., Lyubarskaya, Y.L., DesOrmeaux, J.S., Taylor, J.G., Gaborski, T.R., Shestoaplov, A.A., Striemer, C.C., McGrath, J.L., (2013) Ultrathin Silicon Membranes for Wearable Dialysis, Advances in Chronic Kidney Disease 20: 508-515
  • Salminen A., Hill K, Chung HH, McGrath JL, Johnson DG,(2018) Protein Separation and Hemocompatibility of Nitride Membranes in Microfluidic Filtration Systems. Engineering in Medicine and Biology Society (EMBC),  40th Annual International Conference.


  • Mukaibo, H., Wang, T., Perez-Gonzalez, V., Getpreecharsawas, J., Wurzer, J., Lapizco-Encinas, B., McGrath, J.L. (2018) Ultrathin Nanoporous Membranes for Insulator-based Dielectrophoresis (iDEP). Nanotechnology 29:235704
  • Getpreecharsawas, J., McGrath, J.L., Borkholder, D. (2015). The electric field strength in orifice-like nanopores of ultrathin membranes. Nanotechnology 26: 045704
  • Snyder, J.L., Getpreecharsawa, J., Fang, D.F., Gaborski, T.R., Striemer, C.C., Fauchet, P.M., Borkholder, D., and McGrath, J.L. (2013) High performance, low voltage electroosmotic pumps with molecularly thin nanoporous silicon membranes, Proceedings of the National Academy of Science 110:18425-30


  • Mireles, M., Soule, C.W., Dehghani, M., Gaborski, T.R. (2020) Use of Nanosphere Self-Assembly to Pattern Nanoporous Membranes for the Study of Extracellular Vesicles Nanoscale Advances, Adv. Article, 10.1039/d0na00142b
  • Wright, E., Miller, J.J, Csorda, M.. Gosselin, A.R., Carter, J.A., McGrath, J.L., Latulippe, D.R., Roussie, J.A. (2020) Development of Isoporous Microslit Silicon Nitride Membranes for Sterile Filtration Applications Biotechnology & Bioengineering 117:879-885
  • Madejski, G., Lucas, K., Pascut, F.C., Webb, K.F., McGrath, J.L., (2018) TEM Tomography of Pores in Silicon Nanomembranes. Membranes 8: 26-38
  • Mireles, M., Gaborski, T.R., (2017) Fabrication Techniques Enabling Ultrathin Nanostructured Membranes for Separations. Electrophoresis 38: 2374-2388.
  • Gilmer, S.R., Fang D.Z., Wayson, S.E., Winans, J.D., Abdolrahim, N., DesOrmeaux, J.P.S, Getpreecharsawas, J., Ellis, J.D., Fauchet, P.M., McGrath, J.L., (2017) Predicting the failure of ultrathin porous membranes in bulge tests, Thin Solid Films, 631: 152-160
  • Li, X., Johnson, D., Ma, W., Chung, H., Getpreecharsawas, J., McGrath, J.L., Shestapalov, A.A., (2017) Modification of Nanoporous Silicon Nitride with Stable and Functional Organic Monolayers, Chem. Mater., 29: 2294–2302
  • Miller, J. J.; Carter, R. N.; McNabb, K. B.; DesOrmeaux, J. P. S.; Striemer, C. C.; Winans, J. D.; Gaborski, T. R., (2015) Lift-off of large-scale ultrathin nanomembranes. J Micromech Microeng 25: 015011.
  • Qi C, Striemer CC, Gaborski TR, McGrath JL, Fauchet PM. (2015) Influence of Silicon Dioxide Capping layers on pore characteristics in nanocrystalline silicon membranes. Nanotechnology 26: 055706
  • DesOrmeaux, J. P., Winans, J. D., Wayson, S. E., Gaborski, T. R. , Khire, T. S., Striemer, C. C., and McGrath, J. L. (2014) Nanoporous silicon nitride membranes fabricated from porous nanocrystalline silicon templates, Nanoscale 6:10798-10805
  • Qi C, , Striemer CC, Gaborski TR, McGrath JL, Fauchet PM. (2014) Highly Porous Silicon Membranes Fabricated from Silicon Nitride/Silicon Stacks. Small 10:2946-53
  • Marko, M.; Meng, X., Hsieh, C.; Roussie, J., Striemer, C., (2013) Methods for testing Zernike phase plates and a report on silicon-based phase plates with reduced charging and improved ageing characteristics. J Struct Biol, 184 (2), 237-44.
  • Fang, D.Z., Striemer, C.C., Gaborski, T.R., McGrath, J.L. and Fauchet, P.M. (2010) Methods for controlling the pore properties of ultra-thin nanocrystalline silicon membranes J. Phys. Condens. Matter 22:454134-41
  • Fang, D.Z , Striemer, C.C., Gaborski, T.R., McGrath, J.L., and Fauchet, P.M., (2010). Pore Size Control of Ultra-thin Silicon Membranes by Rapid Thermal Carbonization. Nano Letters 10:3904-8
  • Striemer, C.S, Gaborski, T.R., McGrath, J.L., Fauchet, P.M, (2007) Size and charge based separation of macromolecules using ultrathin silicon membranes, Nature 445:749-53