We borrowed a method first published by Jahn et alii about 7 years ago, in which lipid dissolved in ethanol are streamed through a central channel and compressed by 2 streams of  buffer (we used PBS).  This hydrodynamic focusing results…

In this post I address every objective we started with and summarize our results: a) Building of research capacity at Fisher. —–> We would like to to produce our lipid-based nano particles in a cheaper and more reproducible way. For the…

In our previous post I relate how our first experience with the membranes encountered some difficulties.  These were mostly of two kinds:  clogging or braking of the membrane and somewhat arbitrary sizing of the particles.  We think we have fixed…

Josh has just started teaching us how to play with these; some early findings: – So far, standard centrifugation results mostly on the caking of lipids that clogs the membranes. – Use of the pressure cell has shown some promise,…

We still have plenty of things to do, but after five weeks working at the UR, we have come a long way: – Chip production for instructional use:  done – Design and production of SU8 mold: done – Protocols for (@Fisher)…

MAKING CHIPS We now have our own SU-8 mold (with the help of Brian & Alex at URnano) and have started producing chips (see below) with our channel designs.  Together with the chips produced last week, we have accomplish one…

HI everyone, We continued working with Henry and Greg, gaining expertise on building chips and print-cutting channels.  Right now we have a bunch of chips made, some have been tested, and we have completed one of our objectives : To…

With the help of Henry and Greg, the Fisher team has been busy learning the basics.  John and Ryan have learned some PDMS microfluidics-making and will have their first chips ready on Tuesday.  We have also been playing with the…

The overarching goal of this collaboration is to expose students and faculty at primarily-undegraduate institutions to the technology & expertise available at the University of Rochester.  We would like to make this kind of experience a recurring theme at URNano,…

Hello NRG! Thanks to Jim McGrath and NSF, St. John Fisher College students and myself will have the opportunity to conduct research at URNano and the McGrath Lab this summer.  I am an Assistant Professor at Fisher in the Biology…