Author: Jim
Professor McGrath holds a BS degree in Mechanical Engineering from Arizona State and a MS degree in Mechanical Engineering from MIT. He earned a PhD in Biological Engineering from Harvard/MIT's Division of Health Sciences and Technology. He then trained as a Distinguished Post-doctoral Fellow in the Department of Biomedical Engineering at the Johns Hopkins University. Professor McGrath has been on the Biomedical Engineering faculty at the University of Rochester since 2001 where he also served as the director of the graduate program in BME for more than a decade and currently serves as Associate Director of the URNano microfab and metrology core. Professor McGrath also has faculty affiliations with many other programs at UR including the Material Research Program, the Environmental Health and Sciences Center, the Biochemistry and Biophysics program, and the Musculoskeletal Research Center. McGrath's graduate, post-doctoral, and early faculty research was focused on quantitative experiments and mathematical modeling of cell migration covering molecular, cellular, and multi-cellular phenomena. This was true until 2007 when he, along with Professor Philippe Fauchet (now Dean at Vanderbilt) and PhD students Tom Gaborski (RIT) and Chris Streimer (Adarza), discovered a means to self-assembled nanopores in 15 nm thick free-standing silicon and demonstrated the remarkable transport properties of the new material in a Nature paper. This seminal discovery led to the creation of the multidisciplinary Nanomembrane Research Group (NRG) and the founding of SiMPore Inc. in the same year. The NRG and SiMPore have been dedicated to the advancement of ultrathin membrane technologies and exploring all of their potential applications ever since. This blog also dates back to 2007 and has had contributions from more than 100 students, faculty, scientists, engineers, and entrepreneurs. It contains over 2,500 pages and posts logging progress large and small over all these years. Yet somehow it feels like we are just getting started.

Congrats Dave!

PhD Dec. 15, 2010 Thanks for Everything!

Posted in NRG

Diffusion boosts sieving coefficients in dead-end filtration through pnc-Si

One of the features of the gold nanoparticle separations in SepCons that was under-appreciated by the reviewers at Science was the fact that we could get very high sieving coefficients in the neighborhood of the cut-off. For 5nm gold the

Posted in NRG

Tom's Latest Gold Separation Figure

I asked Tom to add gold PES separations of NPs to his earlier figure and to evaluate the loss of NPs during the use of these filters compared to pnc-Si. Here is what he came up  … All experiments (including

Posted in NRG

SiO2 evaporation at RIT

Today Barrett and I processed SiO2 deposition at RIT. This process was actually delayed due to the cleanroom scrubber failure last week. We deposited 30nm SiO2 on both sides of three wafers, #335, 341, and 345. Earlier in March, I

Posted in NRG

Spectrophotometer raw data

Upload just for future reference. This includes the data of KMnO4 serial dilutions absorbance and the stir cell diffusion experiment.

Posted in NRG

Stir Cell KMnO4 Diffusion Curves: strange and interesting

I got three pinhole-free membranes from Karl after the inspection. They are from wafer#612. Locations are (-3, 1), (-3, 2), and (-3, 3). I used the UV/Ozone machine to oxidize and charge two of them while leaving the third one

Posted in NRG

KMnO4 as a Platform: absorbance vs. concentration

I discussed with Jess the possibility of using a negatively charged dye. People did use such dyes before but we probably need to order them at this time. Since now we can use the spectrophotometer to determine the concentration of

Posted in NRG

Plasma oxidation of Si membrane

As Jim suggested, we are not only going to reproduce what Chris and Tom did in the Nature paper but also trying to test the charge screening effect based on different salt concentrations. To do such experiments, we need to

Posted in NRG

Cell Culture Applications

I’ve added a page on cell culture applications to the knowledge wiki. Watch this page and edit it if the topic is of interest to you. Remember the wikis provide a place to comment on the changes you make …

Posted in NRG

DI water buffer or thiol passivation?

I hope to bring this question to our group meeting. As we discussed before, we know that Cl- can be absorbed at the gold surface to screen the applied positive charge. We are using R6G as the filtration species, which

Posted in NRG
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