Author: Karl Smith
Karl is the 'separations czar' for NRG. As a Biophysics Ph.D. Candidate, Karl has the responsibility of characterizing new membranes, modeling the unique physics of nanomembrane separations, and finding ways to apply pnc-Si technology to protein purification, nanofluidic transistors, and human hemodialysis. Karl graduated from Allegheny College in 2011 with a double major in English and Physics.

The effects of driving pressure on sieving behavior in SiN Sepcons

We’ve been wondering for some time just how the thinness of our membrane will affect the concentration polarization behavior of solutes. Because solutes with sieving coefficients less than 1 are (by definition) moving slower than the solvent around them, in

Posted in NRG

Assembly statistics for SiN wafers 1070 and 1081

I’ve been on a Sepcon assembly binge, and I thought I would post my assembly statistics. On 12/15/13 (assembly “L”) I broke 28 chips out of wafer 1070. 3 chips were visually damaged by the break-out process, 1 was already

Posted in NRG

Organic-Inorganic Hybrid Membranes Formed from Block Copolymers and Titanium Dioxide Nanoparticles (A Review)

The Wiesner lab at Cornell (whom you may remember as the discoverer of the neutrally charged but highly fluorescent “C-dots” Jess used for her charged-based separation work) are about to publish Asymmetric Organic-Inorganic Hybrid Membrane Formation via Block Copolymer-Nanoparticle Co-Assembly in Nano letters.

Posted in NRG

Zetapotential of untreated pnc-Si varies with pH

EDIT – 2/10/14 – Adding 1 mM phosphate buffer fixes the problems outlined in this post. I’ve been having some trouble taking consistent pH measurements with the new pH probe. Prior to Thanksgiving I made a spectrum of 10 mM

Posted in NRG

Zetapotential Measurements of pnc-Si, SiN, and Stripped SiN Membranes

My streaming potential device is now working consistently. It turns out that the problem was the concentrations of salt that I was using. The Debye Length (the distance over which charge-charge interactions are important in an electrolyte) is given as

Posted in NRG

Streaming Potential Revisited

After last week’s post detailing the problems I’ve been having with my streaming potential setup, Jirachai was kind enough to come by the U of R last friday to look at my device. We banged our heads into the wall

Posted in NRG

Drifting and Biasing Potentials in the Electrodes Make Streaming Potential Measurements Difficult

A few weeks back I had finished my streaming potential/electro-osmotic pump setup. It looks like this: For streaming potential measurements, we pressurize a tube filled with 100mM KCl that connects to the membrane and measure the voltage drop across the

Posted in NRG

Variable Pressure/Speed Experimental Plan

Back when I first joined the lab I did some experiments where I varied the pressure driving a gold filtration experiment. The critical plot was this:   It seems unlikely that the sieving coefficient could change so dramatically with applied

Posted in NRG

Karl’s Streaming Potential/EO Device

I’ve been working on building a streaming potential/EO device for a while now. This was Yaron’s prototype: Which itself was based on Jess’s design: I didn’t like that the device needed to twist together, and also that it was designed for

Posted in NRG

Toward an SOP for working with gold nanoparticles

We’ve been using gold nanoparticles (available for ~80 for a 25mL bottle from Sigma Aldrich in sizes up to 400 nm) for years in the lab. This post highlights some of the previous work that has been posted to the blog and

Posted in Knowledge
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