In previous experiments where the affinity based capture of EVs in ALine devices was tested, issues were encountered. It was noticed that when capturing EVs on the ALine, the non-biotinylated slit membranes had captured a higher quantity of EVs compared…

This post is a continuation of the affinity based capture of streptavidin conjugated EVs. The difference is that instead of using the tangential flow system we used the ALine devices. Sam’s previous work discussed the use of ALine devices for…

Introduction Proliferation, invasion and metastasis of cancer cells require bidirectional cell-cell communication. Cell-cell communication involves the secretion of oncoproteins, mRNAs, RNAs and DNA fragments by cancer cells. The particles that get secreted by these cancer cells are encapsulated in extracellular…