From Jess’ manuscript … From Wikipedia … From Tom’s ACS nano paper … The Dagan equation (2) for flow through short pores used to predict flow through pnc-Si is given by: where r is the average pore radius, DP is…

Vaccinex has developed an antibody, VX15/2503, for Semaphorin 4D, a molecule implicated in axonal guidance mediation and blood brain barrier (BBB) disruption.   The role of SiMPore in its partnership with Vaccinex is to produce a workable model of the BBB,…

One of the surprising results of Jiracai’s studies with thick and thin membranes was that the thicker membranes had a lower capacity to support back pressure than the thinner membranes he used (see table in this post). This is counter…

As discussed in a previous post “Clearance, Kt/V, and Concentration…”, we will use the Kt/V metric to measure the effectiveness of dialysis. There are other methods that are used: one of these is the Urea Reduction Ratio, URR.  URR is…

Jirchai summarized his data in this table … A question raised by a reviewer of our PNAS submission – and one that we’ve had for a long time – is what is the efficiency of the pump. The electrical power…

Dialysis Rate: 10 mL/min, Péclet Number: 1, Membrane Width: 700 µm, Channels per chip: 17 Péclet number Pe ∝ H Pe ∝ 1/L Pressure Drop, P P ∝ 1/H3 P ∝ L

When we submitted the EO paper way back one of the reviewers made the following comment … What is the “head pressure” P_max, i.e. the maximum back pressure that would stop the pump? For any linear electrokinetic phenomenon such as…

The urea assay is straight forward. 6 wells are filled with 0, 1, 2, 3, 4, and 5 nmol of the urea standard (50 nL). Each well is activated with 50 nL of the reaction mix. Reaction Mix Sample control…

In my previous post of Morphology evolution in pnc-Si membrane (2), see https://trace-bmps.org/datablog/?p=14769&preview=true , I showed that membranes (30SiN-25Si-30SiN) annealed at 700C show us an intermediate morphology in the pnc-Si membrane. I did some further investigation in the past week…