Author: Michelle Trempel

Modeling pericyte loss in CNS disease using the µSiM platform to understand post-operative delirium superimposed on dementia – Michelle’s MPS Talk

MPS 2024

Posted in NRG

Using Dual-Scale Membranes as a Model for a ‘Leaky’ BBB

Introduction Many neurodegenerative diseases, including Alzheimer’s disease and Parkinson’s disease, are associated with an early breakdown of the blood brain barrier (BBB). This includes an increase in permeability and pericyte degradation [1]. We hypothesize that using dual-scale (nanoporous and microporous)

Posted in memBrains

Little Back Dots in Coated Controls … How We Wonder What You Are.

Introduction We are investigating some issues seen with long term attachment (up to 6 days) of the EECM-BMEC-like cells seen by collaborators in Bern, where they noticed black aggregates on the coated control devices that get worse at day 6.

Posted in memBrains, NRG
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