SLAS – Society for Laboratory Automation and Screening https://www.slas.org Annual Conference February 6-8, 2017 in Washington DC Attended by Tom Gaborski for informative purposes. Collaborators/colleagues in attendance: Vinay Abhankar (UT-Arlington), Andrea Mazzocchi (alum @ Wake Forest), August Allen (alum @…
Author: Thomas Gaborski
MANUSCRIPT REVISION: Membrane pore spacing can modulate endothelial cell-substrate and cell-cell interactions
Membrane pore spacing can modulate endothelial cell- substrate and cell-cell interactions (REVISION) We submitted our “focal adhesions” paper to ACS Biomaterials Science and Engineering late last year. We received reasonable reviewer requests from three reviewers. I think I am mostly…
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BMES 2016 Presentation: SiO2 Membranes & Cell-Substrate Interactions
Here is a PDF of the presentation I plan to give at BMES this year. The presentation is first an overview of our SiO2 membranes for cell barrier and co-culture models and then a brief summary of our cell-substrate and…
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F-actin alignment on microporous SiO2 membranes
In our study of endothelial fibronectin fibrillogenesis and FA formation on microporous SiO2 membranes, we decided to investigate whether the pore orientation and pore spacing induced FA formation and therefore F-actin alignment. (Note: we updated our last post on FN…
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Investigating the endothelial basement membrane formation on SiO2 membranes
In our prior work we showed that endothelial cells form far fewer focal adhesions on microporous SiO2 membranes compared to non-porous SiO2 and tissue culture plastic (see prior post by Ana). We performed this analysis at 24 hours, which seems…
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Journal Club: Residual matrix from different separation techniques impacts exosome biological activity
Residual matrix from different separation techniques impacts exosome biological activity (PDF) Lucia Paolini, Andrea Zendrini, Giuseppe Di Noto, Sara Busatto, Elisabetta Lottini, Annalisa Radeghieri, Alessandra Dossi, Andrea Caneschi, Doris Ricotta & Paolo Bergese. Scientific Reports 6, Article number: 23550 (2016) doi:10.1038/srep23550 Abstract…
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Brainstorm: Extracorporeal Liver Support
The purpose of this post is to start a general discussion around the idea of using ultrathin silicon-based membranes and graphene oxide to improve Extracorporeal Liver Support, also called Artificial Liver Support (ALS) for patients with acute liver failure (ALF).…
Posted in Knowledge
ICNMM 2016 – Transport in Membranes and Nanofluids (July 10-14, 2016)
Based on the talk I gave at the ICNMM (International Conference on Nano, Micro and Minichannels) this past summer, I’ve been asked if I would organize and chair a session titled: Transport in Membranes and Nanofluids. I’d like to include people…
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Journal Club: Sandwich Microenvironment For Cell Culture
Attached is a paper I’d like to review on Thursday (June 11, 2015). This group is using two planar surfaces in an attempt to mimic a 3D cell culture environment. This is similar to our claims that cells growing on…
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ADSC Migration to HUVEC network (4 hr timelapse)
This is more work that Randi did looking at ADSCs migrating towards HUVEC networks. Motivation: To demonstrate the migration of ADSC toward pre-formed HUVEC networks when ADSC are seeded 4 hours after HUVEC. Method: Monday – Coat 4 wells…
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