Overview of Experiment This experiment examined the behavior of the sieving coefficient graph under mixed particle size conditions, where one particle was significantly greater than the average pore diameter, and therefore acted as a “plug” for the larger pores. With…

To image the blood side (in-channel) side of the membranes, I transferred the membranes of a HD chip onto another wafer segment (SiN wafer: 4534) The transfer wasn’t clean but I got some good images. These membranes were exposed to…

The laboratory has been using our Langer peristaltic pumps for flow experiments in devices with saturated cell culture. A problem we’ve been having with microporous membranes was the shearing of the cells off it, which was attributed to the deflection…

This data comes from our collaborators in Switzerland who are working on a BBB culture model using NPN. In this study they are looking at the effects of co-culture on barrier function. The co-culture is with pericytes and a vascular…

In light of technical difficulties associated with the current liftoff device design, I’ve been working on a slight alteration to the design with an eye towards reducing leaking and improving the shape of the flow in the dialysate chamber. The shape…

LabChip_20160430

Hello everyone,   After some work on GoDaddy’s side, we have fixed the HTTP error when trying to upload images. Please let me know if you encounter this issue in the future. Cheers!

While experimental results are still forthcoming, I thought I’d make a post about the nature of the model I’ve constructed for ECMO. This model is the one that my experiments are seeking to validate; so to be clear, this model…

I attempted to clear the large format lift-off devices (from Josh). I was unable to clear, in a reasonable amount of time (< 2 hours) by pumping IPA. So I switched to PBS then Blood and blue-dyed PBS (dye is…

From my last blog post, was talked about designing an assay whereby the NPN filter would exclude DNA-conjugated gold nanoparticles while allowing short DNA to pass. Since then, I (with the help of my colleague Dan Tassier) have been wrestling…