I’ve been trying for a year now to make a nanofluidic transistor – a nanomembrane with a thin layer of metal coated in dielectric that allows for the dynamic modulation of the sieving characteristics of the chip. Beginning with the…

All separations are 30 nm (diameter) gold nanoparticles in a 56 nm pore setup, with other parameters as described in my last post. Y-axis scale bar is in meters, x-axis scale is meaningless (the simulation is 1-D, and the width…

I have wondered if it were possible to create free-standing, nanoporous nanomembranes out of other materials (rather than my MgF2 process). The process is general enough that it should work. The major factors are Etch Selectivity between the substrate and…

These curves were all generated using the following package of matlab functions and scripts: (Sieving copy – run Find_Sieving_Coefficient_boltzmann.m – it’s set up to generate concentration profiles right now). The program begins with a ‘standard separation’ that uses the following characteristics: Pore diameter:…

After a great deal of debugging and thought, I’ve made a small breakthrough in the modeling of sieving behavior using MATLAB, Bill Deen’s electrostatic model of pore-particle interactions, and a boltzman distribution to model concentration polarization (previous blog posts: Part…

We wanted to prove our previous findings that ADSC crawl toward HUVEC networks and alter them. We did this by using time lapse imagery to demonstrate the migration. We also wanted to show the process of HUVEC network formation. We…

Sometime in September, the group received the following invitation to write a book chapter: We, John Rogers from the University of Illinois at Urbana-Champaign and Jong-Hyun Ahn from Yonsei University, are editing a book that will be published by Wiley-VCH…

Hi All, just a quick post to up date you on what we are up to. 3 Things going on in the lab: Ryan continues to make his nano particles using chips, he is loading them with an anti-inflammatory agent…

Hi all, Presented here is a prototype of an “all purpose” SiN chip system for use in cell studies. The reason it was called “all purpose” because it is intended for simple cell culture and migration/chemotaxis studies. This prototype is…

I went to Kidney Week in Philly, Nov 13-15. American Society of Nephrology. I spent most of my time in the Bioengineering talks and posters. Here are some highlights. I put the Abstracts pdf on the cloud. Recellularization of Vascular…