Transendothelial electrical resistance measurements are expressed in the units . Where the measured resistance is multiplied by the area of the membrane to enable a comparison between measurements in different systems. We have often wondered why, but the reasoning for…
Category: NRG
NPN as an integrated filter for a NP Sensor
Last fall we decided to try to integrate a filter immediately upstream of Vincent Tabard-Cossa’s nanopore DNA sensors. The idea is to assemble back-to-back a NPN membrane a standard nitride membrane used in Vincent’s nanopore fabrication system an oxide spacer.…
Posted in NRG
Integrated Electroosmotic Nanopumps on a Chip
As part of my thesis work, I hope to create modular pumps and flow sensors using silicon nanomembrane technology. Devices that could generate/detect microliter and nanoliter scale flows would decrease the overall size of microsystems, replacing larger micropumps (pneumatic PDMS, Chip-sized…
Posted in NRG
Adding a Compressible Cake Layer to the Theoretical Model
In a previous post (linked here), I discussed a naïve way to incorporate concentration polarization into our theoretical model of the sieving of charged nanoparticles. Essentially, I considered the particles to be uncharged point particles that were subject to a…
Posted in NRG
Surface Modification for Hemodialysis
We are continuing to work with the Shestopalov lab on surface modifiation of hemodialysis filters to prevent adhesion and activation. Jim recently presented our status and strategy (PDF) to the Technical Development Fund and was awarded the balance of the award,…
Error made when assuming identitcal pore size during simple flow modeling
Hi all, Sometimes for flow modeling I assume all pores to be identical in size. However, since larger pores allow much higher passage of flow, the above assumption will generally underestimate the prediction of flow. Presented here is a…
Posted in NRG
Summary of recent changes
The blog has migrated to a new hosting provider. This means that the passwords for owncloud and the blog are no longer in sync. Owncloud has been upgraded from 5.0.18 to 7.0.4. The passwords have not been changed and are…
Posted in NRG
Initial MgF2 Nanomembrane Cytocompatibility Study (Live/Dead)
I want to verify that I can grow a confluent monolayer of cells on my MgF2 nanomembranes. I have tried to do this in the past, but have only gotten sparse cells overall before the membranes ruptured. I believe that…
Posted in NRG
ADSC Migration to HUVEC network (4 hr timelapse)
This is more work that Randi did looking at ADSCs migrating towards HUVEC networks. Motivation: To demonstrate the migration of ADSC toward pre-formed HUVEC networks when ADSC are seeded 4 hours after HUVEC. Method: Monday – Coat 4 wells…
Posted in NRG
Two ways to subscribe to the blog
There are now two ways to sign up to receive new blog content by e-mail. The original way was disabled for a few months, but is now back. This is the approach that creates a beautiful e-mail with full post…
Posted in NRG
