We’ve completed two successful 4-hour small animal hemodialysis experiments. I’ve also analysed the serum from all previous experiments. This graph shows only the recently analysed serum and doesn’t include the previously analyzed data. I’ll give a more detailed analysis of…

In order to prevent membrane breaking, I rebored the acrylic plates for larger bolts and added compression springs to regulate the clamping force on the chips. I also flushed the devices at the vivarium where the animal experiments take place. There…

(UPDATED with n=4) I’ve repeated the burst pressure experiments performed by Sabrina, with the 75 nm thick hemodialysis chips. The previous chips are 50 nm with a burst pressure of 1.5 psi (10.5 kPa). I found the burst pressure of the 75…

Sabrina’s post showed that on a bench top, with ‘blood’ source and return at ATM, the transmembrane burst pressure was between 0.5 psi and 1.5 psi, (initial and after DI or PBS flow for four hours). Extrapolating from Burst pressure chip tests for the…

This post is from Xuan ‘Sabrina’ Pan Purpose The nanomembrane used in my experiments is expected to promote efficiency of hemodialysis (HD) for end-stage renal disease patients. The membranes, however, broke during HD for rats, and breaking membranes can lead…

Here are the Vascular Interviews in comma separated value form if you want to download them. Here is what I learned or had reinforced. An arteriovenous fistula (AVF) is the preferred method for creating an easily cannulated access point to large volumetric blood flow…

In order to investigate the breakage of nanoporous nitride hemodialysis chips during rat dialysis, we are investigating the pressures in the system. We will investigate normal operating pressures as well as potential impulse pressures from handling or valve operation. To…

My original post reported burst pressures on rectangular windows with the chips trench side down in the fixture (pressure from below). These values are low compared to square window pressures. My pressures ranged from 2 psi to 12 psi while square windows achieved…