Dialysis Rate: 10 mL/min, Péclet Number: 1, Membrane Width: 700 µm, Channels per chip: 17 Péclet number Pe ∝ H Pe ∝ 1/L Pressure Drop, P P ∝ 1/H3 P ∝ L
Author: Dean Johnson
Dr. Johnson is a Research Assistant Professor in Nephrology who was awarded an R01 in 2020. He earned his Ph.D. in Microsystems Engineering from RIT and is currently working on hemodialysis devices based on the ultrathin nanoporous membranes developed earlier by this group.
Urea Assay Standard Curve
The urea assay is straight forward. 6 wells are filled with 0, 1, 2, 3, 4, and 5 nmol of the urea standard (50 nL). Each well is activated with 50 nL of the reaction mix. Reaction Mix Sample control…
Posted in NRG
Clearance, Kt/V, and Concentration in a Reverse Flow Dialyser
Instantaneous Clearance: Kd CBi, and CBo are the concentration of solute in the blood at the input and output of the dialyser. CDi and CDo are the concentration of solute in the dialysate at the input and output. QBi, QBo,…
Posted in Knowledge, Knowledge (Public)
Microfluidics in Hemodialysis Project
The purpose of the fluidics in our hemodialysis system is to move the sample to and the retentate away from the membranes. The dialysate (permeate, filtrate) will be handled passively in the initial designs and therefore do not require fluidic…
