Summary: The fabrication of NPN relies on the formation of pnc-Si over a non-porous SiN film, then etching the pattern of the pnc-Si into the SiN. I used the same concept to replicate the dual-scale nanomembrane style (microporous+nanoporous) featured in…
Category: NRG
Compressive Structured Illumination Microscopy (CS-SIM)
I would like to introduce Compressive Structured Illumination Microscope (CS-SIM), which will be built in the McGrath’s Lab. CS-SIM is a novel microscopy framework, which was proposed by me. It is dedicated to alleviate some SIM problems such as motion…
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Microtechnologies for cells an devices – BMES 2019
Microtechnologies for cells Phototunable Spatiotemporal Presentation of Viscoelastic and Adhesive Cues in HA Hydrogels Erica Hui1, Kathryn I. Gimeno2, Thomas H. Barker2, Steven R. Caliari1,2 Department of Chemical Engineering, Department of Biomedical Engineering, University of Virginia https://www.biorxiv.org/content/10.1101/646778v1.full Developed a hyaluronic…
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BMES 2019 – Cell matrix interactions and platforms for creating engineered ECMs
BMES 2019 saw a number of talks being presented on the topic of controlling extracellular matrix architecture and understanding how cells respond to physical cues from their in ECM. My focus was primarily on talks pertaining to the tumor microenvironment…
Constricted migration (BMES 2019)
Cancer cell metastasis is responsible for 80 percent of cancer-related death. The metastatic cells migrate through tight constricting spaces, therefore constricted migration and its enabling mechanisms have received a lot of attentions in recent years. The most famous research groups…
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BMES 2019 Recap: Organ-on-a-chip models with emphasis on modeling blood-brain barrier
There were lots of interesting talks and posters on organ-on-a-chip models with emphasis on modeling blood-brain barrier. I have selected four of them as a summary. 3D model of diffuse intrinsic pontine glioma growth, migration and blood-brain barrier interactions Alanna…
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Sepsis and Sepsis-Associated Neutrophil Dysfunction – BMES 2019
Introduction Sepsis related projects had a decent presence at this years Biomedical Engineering Society (2019). I will detail a few of the talks I found most relevant to our group and research. Nanomedicine for Acute Criticial Illness by Dr. Jacob…
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Woods Hole Workshop on Microplastics in the Oceans
Summary: Dan and I went to Woods Hole Oceanographic Institute to learn about the current state of microplastics research. There were a number of things that we learned that we did not know. The common sentiment among researchers agreed climate…
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Modular assembly of the µSiM
Design and Manufacturing Plans from Aline: 2019-09-23 Rochester Assembly Step by Step Prototype Runs @ ALine Post-fabrication assembly (cutting with lower power to eliminate bubbles) …
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STED Imaging of Silica Beads
To try to calibrate the STED for imaging on our membranes, Bill and I have been trying to use 50 nm silica beads that have been captured on the membrane. However, we discovered initially that the beads were actually not…
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