Category: NRG

Sepsis and Sepsis-Associated Neutrophil Dysfunction – BMES 2019

Introduction Sepsis related projects had a decent presence at this years Biomedical Engineering Society (2019). I will detail a few of the talks I found most relevant to our group and research. Nanomedicine for Acute Criticial Illness by Dr. Jacob…

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Woods Hole Workshop on Microplastics in the Oceans

Summary: Dan and I went to Woods Hole Oceanographic Institute to learn about the current state of microplastics research. There were a number of things that we learned that we did not know. The common sentiment among researchers agreed climate…

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Modular assembly of the µSiM

Design and Manufacturing Plans from Aline: 2019-09-23 Rochester Assembly Step by Step Prototype Runs @ ALine Post-fabrication assembly (cutting with lower power to eliminate bubbles) …  

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STED Imaging of Silica Beads

To try to calibrate the STED for imaging on our membranes, Bill and I have been trying to use 50 nm silica beads that have been captured on the membrane. However, we discovered initially that the beads were actually not…

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hiPSC Differentiation to Brain Microvascular Endothelial Cells (BMEC)

INTRODUCTION The blood-brain barrier (BBB) is a highly selective endothelial barrier that serves a crucial role in maintaining tissue homeostasis in the brain. Many current models, however, suffer from low TEER and permeability values far greater than physiological levels. Recently,…

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Confocal Analysis of Apical and Basal ICAM-1 Expression Following Polarized Cytokine Delivery

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Membrane Functionalization: The Pursuit of Chemically Specific Separations

In pursuit of an extremely sensitive biomarker capture sensor, I have been tasked with chemically functionalizing the surface of our membranes. Our end goal is to attach antibodies to the surface of our membranes which can be used to selectively…

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Microvascular Mimetics for the Study of Leukocyte-Endothelial Interactions

Here are the figures for Tejas’ paper that is in the final stage of drafting:

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Nanopocket Membrane Fabrication-Update

 

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JMS Paper Introduction

Silicon nanomembranes are ultrathin, free-standing structures that vary from 10 – 100 nm in thickness. These membranes are at least 1 order of magnitude thinner than the thinnest polymeric membranes. Pores can be manufactured on these membranes to have diameters…

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