As part of my thesis, I am trying to get a non-fouling pattern on a substrate which resembles our porous membranes to investigate cell behavior including cell adhesion and migration and to compare with our previous results which was obtained…
As part of my thesis, I am trying to get a non-fouling pattern on a substrate which resembles our porous membranes to investigate cell behavior including cell adhesion and migration and to compare with our previous results which was obtained…
In my previous post, our urea clearance for the single pass experiments was found to be ~140 ml/min/m^2, which was similar to Fissell/Roy’s value except we used a flow rate of 1uL/min whereas they used a flow rate of 10…
This is a continuation of my post from last time where I looked at modeling actual pore geometries in COMSOL. In this post, I explored the new feature that we have with COMSOL that is the Particle Tracing Module. This…
We have been collaborating with Britta Engelhardt’s group at the University of Bern in Switzerland since Tejas and I met them at the CNS Barriers conference in Paris in 2015. They are interested in studying live T-cell transmigration across human…
We manufactured a wafer specifically for SERS experiments in the hope of recapturing larger pore distributions/pore densities that we observed in some of the prototype runs of NPN. Natively, it’s a little thicker, and a little less porous than the…
Hello Everyone, As you probably know, i have been working on calibration curves for NPN and TE membranes and comparison of these two sets of experiments with each other. This post is all about how i made the calibration curves…
As Greg posted last time, he and I have been working on a manuscript for all of the tomography stuff that we have done that we are going to hopefully submit this week. In that paper, we covered all the…
I drew an approximation of the SiMPore liftoff device and ran the COMSOL model with 1 mL/min urea fluid flow in the upper channels and 2 mL/min dialysate in the bottom channels. With this initial model, the urea was cleared…
We’ve calculated our instantaneous clearance numbers for the benchtop studies that use sepcon chips. Even calculating per unit area, our chips are not clearing much volume in these experiments. I believe this is due to the very low flow rate…
Kilean and I are working on submitting a paper to Membranes on some of our electron tomography work. Here’s some of the work that we’ve done so far: Tomography Paper V2_KL