Background Details: Josh Miller & I have made some recent progress in the NPN LO work.  We had several ø6″ wafers w/ 100 nm of thermal oxide processed by Rogue Valley, wherein they deposited 650 nm of poly-Si (LP-CDV) followed…

These fits are done using the math outlined in this previous post. We assume an average pore size of 50 nm and an approximate number of pores in the membrane of 1E9. 20 nm particles:   100 nm particles:  …

I was not entirely satisfied with the amount of data that I received from my last burst pressure wafer, so I processed another wafer. This wafer had some yield loss initially, as well as window sizes that were slightly smaller…

In my previous post, I derived a formula for the time-dependent flux decline in a centrifuge-driven membrane separation, assuming that the resistance of the membrane was held constant. The problem with that approach is that, as Josh discusses in this…

Kevin Healy is a Phase I and Phase II awardee of the NIH Tissue Chip initiative. The goal of this initiative is to create ‘mini-organs’ ‘organs-on-a-chip’ ’tissue chips’ or ‘microphysiological systems’ (MPS) for higher throughput and more reliable drug discovery.…

I was given three groups of chips to SEM. The first group had undergone the Diazerine and PEG1000 treatment followed by incubation with either PBS, IgG, or BSA. The second ‘group’ was a chip that had been treated with diazerine…

In my recent tenting posts, the membrane has shown that it can deform and wrap around edges. I wanted to follow up on this phenomenon and see if we could get a contiguous sheet of membrane around a PDMS edge (not…

In Josh’s forthcoming paper about clogging in forward and reverse configurations using 20 nm and 100 nm sepcons, we thought there was reason to discuss how the data agrees with the already existing models of membrane fouling. In this post,…

This is a followup to my previous post, which can be found here. Previously I reported that fluorescein diphosphate (FDP) incubated on the surface of an NPN chip would adhere well enough to be visible on the membrane after gentle…

It is of interest to investigate the properties of CO2 transfer into a cell culture media using nanomembrane technologies. Maintaining the pH of the cell culture medium is critical to cell viability. Most cell lines grow well at pH 7.4…