Category: Knowledge

Hemo biometrics for various animals

In determining an appropriate animal model for hemodialysis efficacy, several metrics need to be compared to the human vasculature. Blood volume, blood pressure, and heart rate could effect the suitability of these animals to model clinical hemodialysis. Blood volume can

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Toward an SOP for working with gold nanoparticles

We’ve been using gold nanoparticles (available for ~80 for a 25mL bottle from Sigma Aldrich in sizes up to 400 nm) for years in the lab. This post highlights some of the previous work that has been posted to the blog and

Posted in Knowledge

High Temperature Sepcon Holder Concept

For the upcoming tests I have planned for H2 purification, I need a fixture to hold the pnc-Si membranes (Sepcon format) that is compatible with operation up to 500 C.  No polymers are going to work. I describe the approach

Posted in Knowledge

Scanning ion conductance microscopy of cells on TEM grids (pnc-Si, not annealed)

During the recent visit of Greg Madeijski to our Institute of Biophysics, Imaging & Optical Science (IBIOS) here in Nottingham we had the opportunity to try imaging cultures of cells on several nanoporous membranes, including CytoVu’s and also the unsupported

Posted in Knowledge, NRG

Palladium membrane hydrogen purifier

I have been talking with JP about getting some pnc-Si membranes coated with ~10-20 nm layers of Pd (or Pd-Ag) to do preliminary tests on hydrogen permeation devices. Tom and I are thinking of submitting a proposal. This kind of

Posted in Knowledge

Clearance, Kt/V, and Concentration in a Reverse Flow Dialyser

Instantaneous Clearance: Kd CBi, and CBo are the concentration of solute in the blood at the input and output of the dialyser. CDi and CDo are the concentration of solute in the dialysate at the input and output. QBi, QBo,

Posted in Knowledge, Knowledge (Public)
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