A few weeks ago, Josh and JP brought me some 3 window microslit membranes that had edge aligned 8 and 9 μm slits. While these may seem to be quite large for most applications, they are in fact perfect for working…
Category: NRG
Sacrificial releasing layer and SU-8, plans
This post summarizes a quick update on 2 different goals: 1) membrane releasing and 2) SU-8 strain reduction. Here you will find basic background on some of the work that has already been conducted and the planned experimental work that…
Posted in NRG
HUVEC migration and Fibronectin Fibrillogenesis
Intro: Hi all, as we investigate the formation of HUVEC focal adhesions on porous SiO2 membrane , we also looked at fibronectin fibriollogenesis. Interestingly, it appears that after 24 hr (since the initial seeding), the fibronectin fibrils formed by HUVEC vary…
Posted in NRG
(Almost) Final Versions of Model Paper Figures
We’re submitting the following paper to Separations and Purifications within the next two weeks: model-paper model supplement Below are the (almost) final versions of the figures from the paper. Figure 1: Schematic of Particle Distribution for Particles Rejected by Membranes…
Posted in NRG
Partial Etch RIE Blows out NPN Pores
As the title states, this post is about shifting an arbitrary pore distribution in an NPN layer. Why would we want to do this? We believe that the underlying pore distribution and shape influences the properties of many of our…
Posted in NRG
Final Update over TE membrane
Hello Everyone, So first of all, a quick reminder of what i have been working on: we were able to show the trapping of the beads by TE membranes, although in final step and after releasing of the beads,…
Posted in NRG
Quick Characterization of 3D Printed Reverse Sepcons
Photo Courtesy J. Adam Fenster, U of R We’ve had several of each of the two prototype reverse Sepcon designs professionally 3D printed for us (top photo). I did a few quick tests to see how they worked in the…
Posted in NRG
Rotation Project: The Influence of Collagen Gels and Nanoporous Chips on Shear Based Endothelial Cell Alignment
As an introduction, my name is Alec Salminen. I received my BS in Biomedical Engineering at the University of Arkansas and am currently in my first year of the BME PhD program at the University of Rochester. As my rotation…
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Rotation Project Complete: Dialysis of cytochrome c across a commercial membrane
Dan Steiner Rotation Summary Abstract The purpose of this rotation project was to develop and test a clampable system for eventual use in scalable nanomembrane dialysis systems. The nanomembrane dialysis system will be miniaturized into a compact, wearable hemodialysis device that…
MANUSCRIPT REVISION: Membrane pore spacing can modulate endothelial cell-substrate and cell-cell interactions
Membrane pore spacing can modulate endothelial cell- substrate and cell-cell interactions (REVISION) We submitted our “focal adhesions” paper to ACS Biomaterials Science and Engineering late last year. We received reasonable reviewer requests from three reviewers. I think I am mostly…
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