Here are my slides for presentation at ICNMM. I’m linking them here to facilitate discussion at NRG later today, if desired. .pptx version – ICNMM2016 Presentation Slides .pdf version – ICNMM2016 Presentation Slides
Category: NRG
F-actin alignment on microporous SiO2 membranes
In our study of endothelial fibronectin fibrillogenesis and FA formation on microporous SiO2 membranes, we decided to investigate whether the pore orientation and pore spacing induced FA formation and therefore F-actin alignment. (Note: we updated our last post on FN…
Posted in NRG
Preliminary potentiostat measurements on iBidi format devices
Thanks to Sidahmed Abayzeed and Emilia Moradi. Summary: I’ve started making impedance spectroscopy measurements with a potentiostat in the iBidi devices. The data is noisy, but there is a clear change in the curve characteristic as cells grow upon the nanomembrane.…
Posted in NRG
Reducing intramolecular and interpore translocation kinetics variation by reducing initial entropy
My PhD exam was postponed (tentatively to early September but it’s up in the air still) due to an impending bureaucratic nightmare, so for the last few weeks I have been running more filter experiments, and I have discovered some…
Posted in NRG
IEEE Spectrum: Three Artificial Kidneys…
“Three ways to build an artificial kidney” This IEEE Spectrum article list three efforts to make an artificial Kidney. The first is the AWAK, kidney on a belt. They don’t have the latest images for this, only the original very…
Posted in NRG
ASAIO notes
ASAIO /əˈsī ō/ noun American Society of Artificial Internal Organs. There is an associated Journal, “ASAIO Journal”, and a yearly conference for the presentation and discussion of research relating to advances in medical device technology. While the initial focus of…
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Ultrathin Polymer Membranes with patterned, micrometric pores for organs-on-chip
Paper for Friday’s Journal Club … Watch this space for a summary and analysis. Pensabene(Hofmeister)ACSAMI16 Synopsis 2um(?) pores in 100 nm thick PLLA. Very, very low porosity. Fabricated with a PVA microneedle mold produced with femto second laser. Microfluidic device…
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COMSOL Model Files Download Page
This post is not an update on my research. I am creating this page to house download links to the COMSOL Multiphysics models I’ve constructed in the course of my work here in the McGrath Lab. This page is linked…
Posted in NRG
Solid- State Nanopores Integrated with Nanoporous Membranes for Enhanced Single-Molecule Counting of Low-Abundance Biomarkers
We are putting the final touches on a submission to NIH based on our work with Vincent Tabard-Cossa in Ottawa. I want to provide everyone with a small overview. The basic premise is that solid nanopores (ssNPs) are the right…
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Investigating the endothelial basement membrane formation on SiO2 membranes
In our prior work we showed that endothelial cells form far fewer focal adhesions on microporous SiO2 membranes compared to non-porous SiO2 and tissue culture plastic (see prior post by Ana). We performed this analysis at 24 hours, which seems…
Posted in NRG
