Program C. Gu – Harvard Seminal Experiments Reese and Karnolvsky 1967 Brightman and Reese (1969) Two unique features of CNS endothelium: Specialized tight junctions – Very low rate transcytosis. Tight Junction by EM Ben-Zvi et al 2014 Nature. Transcytosis becomes…

Josh Miller and Elizabeth Hirschman (RIT co-op student working on STTR lift-off project) obtained preliminary successful results lifting off ~1 in2 sections of NPN membrane where the nanopores were only transferred into the nitride layer in a microporous pattern (ø3…

Xingyu et al; Supplement The authors of this submission to ACS Nano apply techniques for the creation of mesoporous silica thin films with vertically aligned nanochannels to create ultrathin (< 100 nm) silica membranes with ~ 2 nm nanochannels. The…

Based on the talk I gave at the ICNMM (International Conference on Nano, Micro and Minichannels) this past summer, I’ve been asked if I would organize and chair a session titled: Transport in Membranes and Nanofluids. I’d like to include people…

Notes from the ECM4 conference Met with Mathew Halls from Schrodinger. He was curious about what I did, came up, gave me his card. Apparently he knows Chin Tang. He’s giving a talk on the last day. Opening Remarks –…

I decided that instead of trying to figure out why it was delaminating, I would simply remove the option altogether.To that end, I painted PDMS on two NPN chips up to the oxide spacer.   Attempt 1: This chip was…

I am doing a few more membrane transfers and trying to troubleshoot my delamination problems, and I wanted to run my protocol by you guys before I mess up any more chips. I was able to get about 3/7 transfers…

Since the control experiments seem to be going OK I decided to try again with one of the NPN-tented structures that Greg made originally. Since piranha cleaning seemed to be making a difference I wanted to pre-clean the chip, but…

Phase II submission August 1, 2016 or January 30, 2017 UR Tasks – Biocompatibility by Feb. 1 2016 Channel design optimization by November 2015

The idea here is to use nano membranes that have been integrated in a chip with the intention to mix otherwise laminar flow streams.   It was suggested at one of the meetings that I should superimpose the streams, then…