I followed Greg’s example and embedded a broken-membrane chip in a PETL.  The idea was to use it as a negative control before I use an intact chip.  Laminar flow should be maintained in this scenario in order for us…

To analyze the dimpled  Sylgard substrates that we’ve been making, we’ve been conducting experiments to investigate how topographical differences in the surface of a substrate impacts HUVECs and ADSCs, in this case the dimples.  We’ve already shown that cells will grow on these membranes in…

Hi all, A while back we have shown that geltrex coating enhances the attachment of HUVEC on SiN membrane . Jim believes that geltrex may be extended an “all-purpose” coating to promote the adhesion of different cell types to the SiN…

We’ve had quite a bit of success transferring nanoporous membranes now, but a lot of questions about the exact nature of the physics at work during the transfer process remain. Pursuant to those questions, we wanted to try changing a variable…

Adding pockets (250 micron long, 76 micron deep) to the bottom of the channel (channel is 500 microns wide, 125 deep) in a 4 layer PETL  (1 inch long chip) promotes disruption of laminar flow.

Recently, SiMPore has been working on a new chip design which involves incomplete etches on both sides in order to create a fluidic system built directly into the silicon, consisting of many long, shallow trenches. These trench chips are designed…

9:10 – 9:55am       Tony Pietropaoli Must drink liters of water but not urinating. Retaining. Massive edema. Cases that recover must absorb 1/3 to 1/2 of all patient deaths in hospital are related to sepsis. May be an…

pdf of Zydney Paper This paper tackles the concept of membrane capacity – the amount of fluid a membrane can pass before it’s flux declines (due to pore blockage or the buildup of a cake) to some arbitrary fraction of…